Residents of Orlando West, Soweto, who included pensioners, burnt tyres and protested against Eskom power cuts on Wednesday.
Johannesburg metro police spokesman Chief Superintendent Wayne Minnaar said the Klipspruit Valley and Khumalo Roads were affected.
”The protesters started at around 7am and are obstructing these roads, we advise motorists to use alternative roads such as Chris Hani Baragwanath and Elias Motsoaledi Roads,” Minnaar said.
The protesters placed rocks and burning tyres on the roads, preventing traffic flow in the area.
On Monday, hundreds of residents in the neighbouring Diepkloof protested over housing, obstructing the area between Chris Hani Baragwanath Hospital and the N12.